Health Condition 1: null- Chronic Idiopathic Urticaria Health Condition 2: L501- Idiopathic urticaria
Conditions
Interventions
Intervention1: Rupatadine: Rupatadine 10mg once daily for 6 weeks
Control Intervention1: Loratadine: Loratadine 10 mg once daily for 6 weeks
Sponsors
SRM University
Eligibility
Inclusion criteria
Inclusion criteria: 1.Man or woman aged between 18 to 65yrs old. 2.Documented history of active CIU (urticaria wheals) for at least three days per week over the last 6 weeks. 3.Active CIU(labeled as moderate pruritus) for at least 3 days (not necessarily consecutive days) in the week before inclusion with a total score of active CIU labeled as at least a moderate severity of pruritus (score>=2) for these 3 days. 4.Those who were willing to participate in the study and comply with its procedures by signing a written informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients suffering from other forms of urticaria, with significant concomitant illness (e.g., malignancies or hepatic, psychiatric, endocrine or other major systemic diseases). 2.Pregnant women, lactating mothers, females on oral contraceptive pills. 3.Patients on antihistaminic therapy for 72 hours, or steroids for one month, were excluded from the study. 4.Patients with Drug Allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improves Total Symptom score(TSS)Timepoint: At the end of 6 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Improves Dermatology Life Quality Index(DLQI), Improve Global Efficacy Score, Observing Adverse drug reaction by Visual Analogue scale.Timepoint: At the end of 6 weeks | — |
Countries
India
Contacts
Public ContactDr F Syed Hussain
SRM University
Outcome results
None listed