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Study of platelet crossmatch in cancer patients

Assessment of platelet crossmatch results by solid phase red cell adherence assay among adult hematooncology patients and its feasibility in a tertiary care oncology centre.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2017/05/008595
Enrollment
50
Registered
2017-05-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Adult patients of any hematological malignancies with history of packed red cell or platelet transfusion support on more than or equal to 2 occasions.

Interventions

None listed

Sponsors

Immucor India Private Limited
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients of any hematological malignancies with history of packed red cell or platelet transfusion support on more than or equal to 2 occasions.

Exclusion criteria

Exclusion criteria: 1) Pediatric patients 2) Patients having fever, infections, sepsis, splenomegaly, Disseminated Intravascular Coagulation (DIC). 3) Patients receiving amphotericin B

Design outcomes

Primary

MeasureTime frame
1 platelet crossmatch result- positive or negative 2 corrected platelet count increment (CCI) and correlation between these twoTimepoint: corrected count increment between 10 minutes to 1 hour of transfusion

Secondary

MeasureTime frame
we are trying to find out the effect of compatibility on post transfusion platelet increment and effectiveness of transfusion. In such multiply transfused patients, if we choose crossmatched platelets obtained right from the beginning, we will be able to get a better post-transfusion CCI. This may reduce the number of ineffective platelet transfusions. Ultimately this can reduce the burden on platelet inventory.Timepoint: after the study is completed(6 months)

Countries

India

Contacts

Public ContactDr Priti D Desai

Tata Memorial Hospital, Mumbai

pranitasontakke18@gmail.com022-24177000

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026