Health Condition 1: null- Adult patients of any hematological malignancies with history of packed red cell or platelet transfusion support on more than or equal to 2 occasions.
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients of any hematological malignancies with history of packed red cell or platelet transfusion support on more than or equal to 2 occasions.
Exclusion criteria
Exclusion criteria: 1) Pediatric patients 2) Patients having fever, infections, sepsis, splenomegaly, Disseminated Intravascular Coagulation (DIC). 3) Patients receiving amphotericin B
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1 platelet crossmatch result- positive or negative 2 corrected platelet count increment (CCI) and correlation between these twoTimepoint: corrected count increment between 10 minutes to 1 hour of transfusion | — |
Secondary
| Measure | Time frame |
|---|---|
| we are trying to find out the effect of compatibility on post transfusion platelet increment and effectiveness of transfusion. In such multiply transfused patients, if we choose crossmatched platelets obtained right from the beginning, we will be able to get a better post-transfusion CCI. This may reduce the number of ineffective platelet transfusions. Ultimately this can reduce the burden on platelet inventory.Timepoint: after the study is completed(6 months) | — |
Countries
India
Contacts
Tata Memorial Hospital, Mumbai