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A Clinical Study on Combined Effectiveness of Oral and Topical Application of an Ayurvedic Medicine - Agastya Ghrita in the Management of Retinitis Pigmentosa

An open label single arm clinical study on the effectiveness of agastya ghrita pana and tarpana in the management of shleshmavidagdha drishti (retinitis pigmentosa).

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/05/008552
Enrollment
30
Registered
2017-05-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Shleshma vidagdha Drishti( Retinitis pigmentosa)

Interventions

Intervention1: Agastya Ghrita: it is a ghee base Ayurvedic medicine which is used for oral intake and Topical ocular treatment. Intervention2: Agastya Ghrita: Agastya ghrita will be given for oral int

Sponsors

Sri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient ready to sign in informed consent form irrespective of sex, and religion. Naktandhata (night blindness) 2. Difficulty in dark adaptation 3. Reduced field of vision 4.Blurredness of vision 5.Visual acuity test revealing reduced visual acuity. 6.Perimetry showing peripheral visual field defect 7. Opthalamoscopic evaluation of Fundus revealing classical triad of Retinitis pigmentosa (arteriolar attenuation, retinal bone-spicule pigmentation and waxy pallor). 8. Pictorial assessment of Retinitis pigmentosa through Fundal photograph

Exclusion criteria

Exclusion criteria: 1.Patients having total blindness. 2.Patient with all kind of diabetic retinopathy and diabetic maculopathy. 3.Patient with pregnancy and lactating period

Design outcomes

Primary

MeasureTime frame
Improvement in nightblindness improvement in dark adaptation improvement of field of vision Visual acuity test revealing visual acuity improving Perimetry showing peripheral visual field changes Fundal pictorial changes Timepoint: 1 month

Secondary

MeasureTime frame
it checks the further deterioration of nightblindness, reduced peripheral visual field and blurredness of vision.Timepoint: 1 month

Countries

India

Contacts

Public ContactDr Deeraj B C

Sri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital

pundanraj@gmail.com9035906765

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026