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USE OF CITRATE VERSUS ACETATE BASED DIALYSATE IN HEMODIALYSIS

COMPARATIVE STUDY OF CITRATE VS ACETATE BASED BICARBONATEDIALYSATE IN HAEMODIALYSIS

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/05/008546
Enrollment
30
Registered
2017-05-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ON MAINTAINANCE HEMODIALYSIS

Interventions

Intervention1: cITRATE DIALYSATE: We conducted a randomized cross over trial to identify whether use of citrate dialysate (CD) for bicarbonate hemodialysis is beneficial compared to regular acetate ba

Sponsors

MANIPAL UNIVERSITY
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: After approval from institutional ethics committee with informed consent, 32 stable end stage renal disease (CKD5D) patients on twice weekly maintenance hemodialysis of five hour duration in the dialysis unit of Kasturba hospital, Kasturba Medical College, Manipal University were enrolled in the study. The inclusion criteria were end stage renal disease patient on maintenance hemodialysis for minimum 3 months duration

Exclusion criteria

Exclusion criteria: Patients with intercurrent illnesses or hospital admissions in the last one month, on heparin free hemodialysis for any reason and irregular for hemodialysis sessions for the last three months were excluded.

Design outcomes

Secondary

MeasureTime frame
The secondary outcomes studied were effect on intradialytic hypotension, acidosis correction and episodes of symptomatic hypocalcemia.Timepoint: 1 YEAR

Primary

MeasureTime frame
The primary outcomes studied were impact of CD in comparison with AD on hemodialysis adequacy, reuse of dialyzer and quality of life. The secondary outcomes studied were effect on intradialytic hypotension, acidosis correction and episodes of symptomatic hypocalcemia.Timepoint: 1 YEAR

Countries

India

Contacts

Public ContactSHANKAR PRASAD N

Kasturba Medical College, Manipal university

shankarmmcmed@yahoo.com9739905443

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026