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To study the changes in the tongue and upper respiratory tract in patients who are to sleep using the two different drugs

Comparison of Dexmedetomidine and Propofol at different sedation depths during drug induced sleep endoscopy â?? A Randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/05/008530
Enrollment
60
Registered
2017-05-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients undergoing sleep endoscopy for obstructive sleep apnea

Interventions

Intervention1: Group D- receives dexmedetomidine for sedation: Dexmedetomidine bolus of 1mcg/kg given over 10 minutes, followed by infusion at 0.5 mcg/ kg/hour -1mcg/kg/hour to achieve the required s

Sponsors

Postgraduate Institute of medical education and research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All ASA I and II patients between the age of 18-60 years scheduled to undergo Drug induced sleep endoscopy

Exclusion criteria

Exclusion criteria: • patients who have undergone previous upper airway surgery for OSA • severe co morbidity (ASA 3 or more) • allergy to dexmedetomidine and propofol • gross mandibular or maxillary deformity

Design outcomes

Primary

MeasureTime frame
Degree of airway collapsibility at different levels of sedationTimepoint: compare the degree of airway collapsibility with Propofol and Dexmedetomidine at different levels of sedation by BIS during Drug Induced Sleep Endoscopy

Secondary

MeasureTime frame
1.cardiopulmonary effects 2. Time to achieve sufficient sedation 3. Haemodynamic response to drugs 4.Side effects and to identify the contributing factors for airway collapsibility.Timepoint: 5 minutes,10 minutes, 15 minutes, 20 minutes, 30 minutes, 40 minutes, 50 minutes, 60 minutes.

Countries

India

Contacts

Public ContactDivya jain

Postgraduate Institute of medical education and research

jaindivya77@rediffmail.com7087008020

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026