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Level of enzymes in gingival fluid and saliva along with rate of orthodontic tooth movement in extraction cases.

To compare the enzyme activity profiles in human saliva and gingival crevicular fluid along with rate of orthodontic tooth movement in accelerated tooth movement to normal orthodontic tooth movement, in extraction cases- A Clinical Prospective Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/05/008496
Enrollment
20
Registered
2017-05-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Bimax protrusion, Dental crowding and protrusion

Interventions

Intervention1: Normal orthodontic tooth movement: Conventional orthodontic tooth movement with premolar extraction with sliding mechanism with 0.22 slot Control Intervention1: Accelerating orthodontic

Sponsors

Dr Gaurav Kumar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Healthy patient without any systemic diseases. Good oral hygiene Patient requiring premolar extractions.

Exclusion criteria

Exclusion criteria: Pregnancy. Smokers. Radiographic evidence of periodontal bone loss.

Design outcomes

Primary

MeasureTime frame
Alkaline phosphates activity in GCF and Saliva Aspartate Aminotransfarase activity in GCF and SalivaTimepoint: At baseline, 7th, 14th,21st and 28th day, 3rd and 6th week, 3rd and 6 month.

Secondary

MeasureTime frame
Rate of tooth movementTimepoint: At baseline, 30th day and 90 days

Countries

India

Contacts

Public ContactDr Neha Agrawal

institute of dental studies and technologies

drsaurabhsonar@gmail.com9810327188

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026