Efficacy of Pregabalin(drug to reduce nerve related pain) and antioxidants combination in reducing pain in chronic pancreatitis(condition due to damage of organ named pancreas) compared to normal regular treatment: a randomised controlled trial

Efficacy of Pregabalin and antioxidants combination in reducing pain in chronic pancreatitis compared to placebo:A Randomised controlled trial

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/05/008492

Enrollment

Registered

2017-05-05

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Chronic pancreatitis

Interventions

Intervention1: TREATMENT GROUP: Treatment group will receive antioxidant and Pregabalin in addition to standard treatment for chronic pancreatitis.Antioxidant preparation will include daily doses of 2

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Chronic pancreatitis- diagnosed by clinical (with Epigastric pain with or without radiation and endocrine/ exocrine deficiency) and/or Imaging (CECT Abdomen) will be included in the study

Exclusion criteria

Exclusion criteria: Age 65yrs,Active Major Depression,Generalised painful conditions other than CP,Pancreatic neoplastic lesions,Cardiac and renal diseases,Use of other anti epileptics, Hypersensitivity to gabapentin/pregabalinPregnancy,Candidates planned for surgery

Design outcomes

Primary

Measure	Time frame
Change in pain scores(visual analog sale and Izbicki pain score) Timepoint: 12 weeks	—

Secondary

Measure	Time frame
Change in no. of painful days,analgesic requirement,quality of life,analgesic requirement,patient satisfaction,number of hospital admissionsTimepoint: 12 weeks	—

Countries

India

Contacts

Public ContactSuresh kumar

JIPMER

drsureshkumar08@yahoo.com9788637893

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 25, 2026