Effect of Probiotic in treatment of GUM disease

Evaluation of efficacy of Probiotic Bacillus coagulans in the treatment of Gingivitis - A Randomized Placebo controlled double blind trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/05/008455

Enrollment

Registered

2017-05-03

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Chronic Generalised Gingivitis

Interventions

Intervention1: "Bacillus coagulans" BD for 14 days.: NIL Control Intervention1: "Placebo" BD for 14 days.: NIL

Eligibility

Inclusion criteria

Inclusion criteria: Both male and female patients aged between 18 and 30 years visiting to Dept of Periodontics, Sri Hasanamba Dental College and Hospital. Patients diagnosed clinically with Chronic Generalised Gingivits. Patients having minimum of 12 natural teeth.

Exclusion criteria

Exclusion criteria: Patients with systemic illness. Patients with known or suspected allergy to probiotic strain. patients allergic to milk and its products. Patients using Probiotic supplements for other reasons. Systemic or Local use of Antibiotics in last 1 month. Smokers and Alcoholics. Pregnant females and Lactating mothers. Patients who are not willing to comply with the study protocol.

Design outcomes

Primary

Measure	Time frame
Effect on gingival health and reduction of bacterial plaque quantitativelyTimepoint: 21 days	—

Secondary

Measure	Time frame
Efficacy of Probiotic Bacillus coagulans in prevention of gingivitis and maintenance of gingival healthTimepoint: 21 days	—

Countries

India

Contacts

Public ContactDr S Ravindra

Sri Hasanamba Dental College And Hospital

nawab.aftu@rediffmail.com9743186962

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026