Health Condition 1: C847- Anaplastic large cell lymphoma, ALK-negative Health Condition 2: C846- Anaplastic large cell lymphoma, ALK-positive Health Condition 3: C84A- Cutaneous T-cell lymphoma, unspecified Health Condition 4: C840- Mycosis fungoides Health Condition 5: C844- Peripheral T-cell lymphoma, not classified Health Condition 6: null- T Cell Lymphoma
Conditions
Interventions
None listed
Sponsors
IIT Mumbai
Eligibility
Inclusion criteria
Inclusion criteria: Adults aged equal to or above 18 years Mature T cell lymphoma with cutaneous involvement Treatment na�¯ve except those who have received only topical steroids Written informed consent
Exclusion criteria
Exclusion criteria: HIV positive patients Co-existent psoriasis or autoimmune disorders Patients on Immunosuppressive therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients with elevated IL-9 level at baseline will be estimated. 2. TH9 cell percentage in skin biopsy at baseline will be estimated. Timepoint: Day 0 | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in the IL-9 levels at completion of therapy or at 6 months whichever is earlier. 4. Correlation of baseline IL-9 level TH9 cells with disease stage and response status. Timepoint: IL-9 level at 6 months, Correlation of basline IL-9 level and TH9 cells with best response. | — |
Countries
India
Contacts
Public ContactDr Hasmukh Jain
TATA MEMEORIAL HOSPITAL
Outcome results
None listed