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Comparison of the effects of blood sampling from the neonate at birth versus blood sampling from umbilical cord on the need for blood transfusion in very premature infants

Effect of umbilical cord blood sampling versus admission blood sampling on requirement of blood transfusion in extreme low birth weight infants.- A Randomized controlled trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/04/008320
Enrollment
76
Registered
2017-04-10
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Extremely preterm infants after birth

Interventions

Intervention1: Umbilical Cord blood sampling: Blood for initial investigations will be collected from the placental end of the umbilical cord Control Intervention1: Admission blood sampling: Blood for

Sponsors

Surya Childrens hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Preterm infants less than or equal to 28 weeks and/or less than or equal to 1 kg birth weight and recruited at the time of birth

Exclusion criteria

Exclusion criteria: 1. History of clinical chorioamnionitis 2. Monochorionic twins/triplets/Quadruplets 3. Anomaly of the cord like true/False knots, Stricture 4. Funisitis of the cord 5. Major congenital anomalies in the infant like Gastroschisis, Exomphalos 6. Rh isoimmnisation 7. HIV positive mother 8. Hydrops fetalis 9. Cord Blood Banking 10. Placenta accreta/Marginal insertion/Battledore placenta/Velamentous insertion

Design outcomes

Primary

MeasureTime frame
Time to first blood transfusionTimepoint: From birth till discharge from NICU

Secondary

MeasureTime frame
Time to 30% reduction in hemoglobin,volume of blood transfused during NICU stay,IVH Grade 3 or 4,Severe hyberbilirubinemia,ROP requiring therapy,Duration of respiratory support,Duration of hospital stay,Incidence of NEC,BPD,Serum Ferritin at 6 weeks,Haemoglobin level at 4 and 6 weeks and at discharge Timepoint: From birth till discharge from NICU

Countries

India

Contacts

Public ContactDr Haribalakrishna Balasubramanian

Surya Children Hospital

priyankadalia5@gmail.com9977222299

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 3, 2026