A clinical trial to find out the effectiveness of probiotics added to denture sticking powder in reducing fungal infection inside the oral cavity in a denture wearing patient and its effect on retention of the denture.

Comparative evaluation of the effect of denture adhesives with probiotics on colony forming units of candida and retention in completely edentulous patients wearing complete dentures. A randomized controlled trial.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/04/008314

Enrollment

Registered

2017-04-07

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K121- Other forms of stomatitis

Interventions

Intervention1: Probiotics,Lactobacillus acidophillus Lactobacillus rhamnosus Bifidobactreium total strength of 10 raised to 8. 3gms of probiotic added to 15gms of adhesives.: patient will sprinkle ad

Eligibility

Inclusion criteria

Inclusion criteria: a.Completely edentulous patients b. Patients who will be not using antibiotics, antifungals or probiotics in any form. c. Patients who will be asymptomatic candida carriers in oral cavity d. Patients who will understand and will be ready to be part of the study

Exclusion criteria

Exclusion criteria: a. Patients suffering from any chronic debilitating disorder b. Inability to understand and be part of the study

Design outcomes

Primary

Measure	Time frame
1. Colony forming unit of candida CFU/ul 2. Retention of upper denture N-cmTimepoint: 5 weeks	—

Secondary

Measure	Time frame
there are no secondary outcomesTimepoint: there are no secondary outcomes	—

Countries

India

Contacts

Public ContactTamanna M Chhabra

Narsinghbhai Patel Dental college and Hospit

drjrpatel33@yahoo.com09824045092

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026