Health Condition 1: O- Medical and Surgical Health Condition 2: null- patients with both knee joint osteoarthritis posted for knee replacement surgery
Conditions
Interventions
Intervention1: Group A: Epidural analgesia with infusion of Bupivacaine 0.125% will be started through epidural catheter at evening before surgery. Rate of infusion will be titrated to achieve a pain
Sponsors
AIIMS Bhubaneswar
Eligibility
Inclusion criteria
Inclusion criteria: After obtaining written informed consent from patients aged 18 â?? 65 years, of both sex, with either no or controlled systemic illness (American Society of Anesthesiologists physical status I-II), who are planned to undergo elective bilateral total knee replacement will be included.
Exclusion criteria
Exclusion criteria: Patients with history of allergy to local anaesthetics and opioids and history of opioid intake, psychosis, already have been on continued analgesics or corticosteroids 24 h prior to surgery, having contraindications to regional anaesthesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| analgesic requirement and pain scoresTimepoint: 1. Total 24 hour analgesic requirement after surgery 2. Pain score will be assessed every hour till 4 hours, every 4 hours till 24 hours post-operatively | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Vital parameters like heart rate and blood pressure 2. length of hospital stayTimepoint: 1. Vital parameters every hour till next 24 hour of surgery 2. days of stay in hospital after surgery | — |
Countries
India
Contacts
Public ContactP Bhaskar Rao
AIIMS
Outcome results
None listed