Killing of harmful germs in the mouth with the help of Coloring agent and visible light

Effect of erythrosine mediated Photodynamic Antimicrobial Chemotherapy(PACT) on Plaque Microorganisms

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/03/008239

Enrollment

Registered

2017-03-28

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Erythrosine and Dental Curing Light: A dental curing light is a piece of dental equipment that is commonly used in dental clinic for polymerization of light cure resin based composites.

Light Dose: 39.82 J/cm2(Topical) Frequency: Only once, Rout of Administration: Topical route Duration: 60 seconds Intervention2: Erythrosine and Dental Curing Light: A dental curing light is a piece

Light Dose: 39.82 J/cm2(Topical) Frequency: Only once, Rout of Administration: Topical route Duration: 60 seconds Control Intervention1: Erythrosine: Erythrosine, also known as Red No. 3, is an organo

commonly used in Plaque disclosing agents and food coloring agent.

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subjects with minimum of 20 sound natural teeth, 2. Male and Female subjects, who had similar plaque scores on the contralateral tooth of the same arch. 3. Available for entire duration of the study.

Exclusion criteria

Exclusion criteria: 1. Presence of orthodontic appliance or more than one incisor with prosthetic crown. 2. Required immediate care. 3. Destructive periodontal disease. 4. Pregnant and breast feeding women. 5. Chronic systemic conditions (heart, kidneys, liver, or infectious diseases including AIDS). 6. Undergoing antibiotic or steroid therapy in the preceding month. 7. History of allergies to dental products or their ingredients. 8. Oral prophylaxis in the preceding month or periodontal treatment in the preceding 3 months. 8. Gross dental caries 9. Fixed and removable partial dentures 10. History or current use of recreational drug

Design outcomes

Primary

Measure	Time frame
Reduction in Dental plaque microorganism is observed in the experimental group.Logarithmic mean and standard deviation of control group with 102 dilutions of aerobic microbial count were found to be 5.34Â± 0.94 and for experimental group, it was 4.47Â± 1.37. Similarly logarithmic mean and standard deviation of control and experimental group with 102 dilutions of anaerobic microbial count were found to be 6.18 Â± 0.66 and 5.64Â±1.008 respectively.Timepoint: 60 sec.	—

Measure

Time frame

Reduction in Dental plaque microorganism is observed in the experimental group.Logarithmic mean and standard deviation of control group with 102 dilutions of aerobic microbial count were found to be 5.34Â± 0.94 and for experimental group, it was 4.47Â± 1.37. Similarly logarithmic mean and standard deviation of control and experimental group with 102 dilutions of anaerobic microbial count were found to be 6.18 Â± 0.66 and 5.64Â±1.008 respectively.Timepoint: 60 sec.

—

Secondary

Measure	Time frame
Reduction of dental plaque microorganismsTimepoint: 30 sec or more	—

Countries

India

Contacts

Public ContactDr Manohara A Bhat Y

SDM College of Dental Sciences and Hospital

kakarlap@hotmail.com9886305999

Outcome results