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DEXAMETHASONE AND TRAMADOL FOR PREVENTION OF SHIVERING IN SURGICAL PATIENTS

COMPARISON OF INTRAVENOUS DEXAMETHASONE AND TRAMADOL FOR PREVENTION OF SHIVERING IN ADULT PATIENTS UNDERGOING GENERAL ANAESTHESIA - A RANDOMIZED DOUBLE BLIND PLACEBO CONTROLLED TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/03/008233
Enrollment
150
Registered
2017-03-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA I and II undergoing any surgical procedure with duration 1-3 hours

Interventions

Intervention1: Dexamethasone: 0.1 mg/kg i.v. diluted with NS upto 10 ml once only immediately after induction of GA Intervention2: Tramadol: 1 mg/kg i.v. diluted with NS upto 10 ml only once immediate

Sponsors

University College of Medical Sciences and Guru Teg Bahadur Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I and II consenting adult patients of either sex, with age ranging from 18-60 years about to undergo elective surgical procedures under GA, lasting between 1-3 hours will be recruited.

Exclusion criteria

Exclusion criteria: 1. Patients with history of myocardial infarction and insufficiency, neuromuscular disorders, hypothyroidism or hyperthyroidism, diabetes or convulsions 2. Pregnant females 3. Patients having pre-operative oral temperature >38°C or 4. Patients with hemodynamic instability, raised intracranial or raised intraocular tension 5. Patients on anti-depressant medication, corticosteroid therapy or allergies to the study drugs

Design outcomes

Primary

MeasureTime frame
Change in the incidence of post anaesthetic shivering (PAS) after administration of dexamethasone and tramadol.Timepoint: till 2 hours postoperatively

Secondary

MeasureTime frame
1. Severity grading of PAS in each group. 2. Incidence of PONV in each group. 3. Severity grading of PONV each group.Timepoint: till 2 hours postoperatively

Countries

India

Contacts

Public ContactJainendra Chauhan

University College of Medical Sciences and Guru Teg Bahadur Hospital

rsramb@gmail.com9868399699

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026