A comparative study of diclofenac skin patch against oral diclofenac for pain control after root canal treatment

The efficacy of transdermal and oral diclofenac for post-endodontic pain control: A Randomised controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/03/008207

Enrollment

Registered

2017-03-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients diagnosed with symptomatic irreversible pulpitis in relation to first or second premolar tooth of either jaw

Interventions

Intervention1: Transdermal Diclofenac patch: Patients will receive post-treatment transdermal diclofenac patch (100 mg) once a day for two days. These patients will also be given Paracetamol (500 mg)

Eligibility

Inclusion criteria

Inclusion criteria: 1. Healthy persons, 18-65 years of age reporting to the Department of Conservative Dentistry and Endodontics, Faculty of Dental Sciences, Bangalore with pain in posterior tooth. 2. First or second premolar tooth of either jaw diagnosed as symptomatic irreversible pulpitis. 3. Teeth that could be treated endodontically in one visit 4. Intraoral periapical radiograph showing intact lamina dura and no periapical radiolucency and absence of anatomical obstacles like calcifications in the canals, and no anticipated procedural difficulties. 4. Patients giving no recent history of any antibiotic or analgesic taken.

Exclusion criteria

Exclusion criteria: 1. Known hypersensitivity to diclofenac. 2. Pregnancy or lactation. 3. Patients with history of asthma or allergy to anti-inflammatory drugs. 4. Patients with active peptic ulceration within the last six months 5. Patients undergoing treatment with other NSAIDs or any other analgesics or corticosteroids during the trial period

Design outcomes

Primary

Measure	Time frame
To evaluate the effectiveness of transdermal diclofenac patch for post-endodontic pain management.Timepoint: After two days, the effectiveness of transdermal diclofenac patch will be assessed.	—

Secondary

Measure	Time frame
To compare the effect of transdermal diclofenac patch against oral diclofenac for post-endodontic pain managementTimepoint: After two days, the effect of transdermal diclofenac patch against oral diclofenac for post-endodontic pain management will be compared.	—

Countries

India

Contacts

Public ContactDr Shivani Mangal

Ramaiah University of Applied Sciences

sylviamathew@yahoo.co.in9844330333

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026