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Comparison between two medicines namely Dexmedetomidine and Lidocaine to Prevent Cough while waking up from General Anaesthesia in Thyroid Gland Surgery

Comparison of Dexmedetomidine and Lidocaine in Preventing Cough During Emergence from General Anaesthesia for Thyroidectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/03/008193
Enrollment
100
Registered
2017-03-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Cough

Interventions

Intervention1: Dexmedetomidine: Administered intravenously as 1 mcg/kg infusion over 15 minutes. It is just once administered dose only. Control Intervention1: Lidocaine: Administered intravenously as

Sponsors

Christian Medical College Vellore
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All adult patients for thyroidectomy ASA I, II, III Patients given consent for the trial

Exclusion criteria

Exclusion criteria: Patients not given consent Baseline Heart Rate Uncontrolled Systemic Hypertension Patients with Tracheomalacia Patients on Antiarrhthmic Drugs

Design outcomes

Primary

MeasureTime frame
Cough During Emergence from General AnaesthesiaTimepoint: At Extubation and at 1, 3, 5, 10, 15, 30 minutes from Extubation—

Secondary

MeasureTime frame
Heart Rate Blood PressureTimepoint: At Extubation and at 1, 3, 5, 10, 15, 30 minutes from Extubation—

Countries

India

Contacts

Public ContactCharles J

Christian Medical College, Vellore.

tonythomson@gmail.com9500242412

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026