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Comparison of two fluids in patient undergoing craniopharyngioma surgery

TO COMPARE EFFECT OF 0.45%SALINE AND PLASMALYTE A USED DURING INTRAOPERATIVE AND POSTOPERATIVE PERIOD ON SERUM OSMOLALITY IN PATIENTS UNDERGOING CRANIOPHARYNGIOMA SURGERY

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/03/008159
Enrollment
30
Registered
2017-03-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with craniopharngioma posted for craniotomy.

Interventions

Intervention1: PLASMALYTE A iv for intraoperative period: Plasmalyte A is iso-osmolar fluid with pH of solution adjusted with sodium hydroxide. The caloric content is 21Kcal/L. Acetate and gluconate i

Sponsors

PGIMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients undergoing craniopharngioma excision by transcranial approach.

Exclusion criteria

Exclusion criteria: 1. Patients undergoing only biopsy, VP shunt/reservoir placement in cases of Craniopharyngioma , transsphenoidal surgery for craniopharyngioma 2. Patients having Diabetes Insipidus /Diabetes mellitus before surgery 3. Patients with renal function abnormality Patients will be allocated randomly into two groups-

Design outcomes

Primary

MeasureTime frame
To compare effects of 0.45% Sodium Chloride and Plasmalyte A used during intraoperative and postoperative period in patients undergoing craniopharyngioma surgery on Serum osmolality ï?? Timepoint: INTRAOPERATIVE PERIOD AT 1HOUR, 2HOUR , 3RD HOUR AND END OF SURGERY AND POSTOPERATIVE PERIOD TILL PATIENT TAKES ORALLY EXCLUSIVELY ï??—

Secondary

MeasureTime frame
To compare effects of 0.45% Sodium Chloride and Plasmalyte A used during intraoperative and postoperative period in patients undergoing craniopharyngioma surgery on serum sodium, incidence of diabetes insipidus and requirement of vasopressin as secondary outcome.Timepoint: 1 year—

Countries

India

Contacts

Public ContactDr Pranshuta

Post Graduate Institute of Medical Education and Research CHANDIGARH

nidhibp@gmail.com7087009525

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026