Benefits of giving allopurinol to the children undergoing open heart surgery for the heart disease which causes blue baby.

Effect of pre-operative administration of allopurinol on postoperative outcomes in patients undergoing intracardiac repair of Tetrology of Fallotâ??

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/03/008121

Enrollment

Registered

2017-03-16

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- tetralogy of fallots

Interventions

Intervention1: allopurinol: Allopurinol dose 10mg/kg. 1st dose 16 hrs before surgery 2nd dose 8hrs before surgery 3rd dose on the morning of surgery 4th and 5th dose in post operative period 12 hrly

Eligibility

Inclusion criteria

Inclusion criteria: paediatric patients with diagnosis of tetralogy of fallots

Exclusion criteria

Exclusion criteria: children with syndrome, emergency cases, compplicated tetralogy of fallots.

Design outcomes

Primary

Measure	Time frame
Mechanical ventilation time, icu stay, inotriopic scores,cardiac index.Timepoint: cardiac index at day 0 day 1 and day 2. intropic scores for day 0 day 1 and day 2 of operation.	—

Secondary

Measure	Time frame
sod,mad and il6Timepoint: biochemical markers will assessed in blood immediately after aortic cross clamp relies, after coming off bypass, on day 1 and day 2.	—

Countries

India

Contacts

Public ContactDr Sachin Talwar

AIIMS

sachintalwar@hotmail.com9868398136

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026