None listed
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
Department of PhysiologyGovernment Medical Colaage Bhavnagar
Eligibility
Inclusion criteria
Inclusion criteria: 1. Subject who gives written inform consent 2. Subjects should belong to the specified age range (18-45 years). 3. They should have regular menstrual cycles of 27 to 35 days as established by history, for at least the past 6 months.
Exclusion criteria
Exclusion criteria: 1. Participant refusal to participate in study 2. Female subjects below 18 years and above 45years 3. Subjects having irregular menstrual cycle. (anovulatory cycle) 4. Subjects taking any medication or hormonal preparations that could alter the menstrual hormonal milieu. 5. Subjects having any physical illness like hypertension, cardiac arrhythmia, TB, diabetes or any other endocrinological disorders. 6. Smokers, alcoholics or those with history of substance abuse. 7. Athletes and those involved in excessive physical activity. 8. Subjects having any disorder which can interfere with the autonomic responses.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sympathetic function test Resting Systolic and Diastolic BP Blood pressure response to standing Blood pressure response to sustained handgrip Parasympathetic function test Resting heart rate Heart rate variation during deep breathing E/I ratio Immediate response to standing 30:15 ratio Valsalva ratio Heart Rate Variability parameters Time Domain Parameters SDNN RMSSD SDNN index SDSD NN50 count pNN50 Frequency Domain Parameters HF LF VLF LF (nor) HF (nor) HF/LF ratio Timepoint: follicular phase - 9-12th day of menstrual cycle secretory phase- 19- 22nd day of menstrual cycle | — |
Secondary
| Measure | Time frame |
|---|---|
| Sympathetic function test Resting Systolic and Diastolic BP Blood pressure response to standing Blood pressure response to sustained handgrip Parasympathetic function test Resting heart rate Heart rate variation during deep breathing E/I ratio Immediate response to standing 30:15 ratio Valsalva ratio Heart Rate Variability parameters Time Domain Parameters SDNN RMSSD SDNN index SDSD NN50 count pNN50 Frequency Domain Parameters HF LF VLF LF (nor) HF (nor) HF/LF ratio Timepoint: follicular phase - 9-12th day of menstrual cycle secretory phase- 19- 22nd day of menstrual cycle | — |
Countries
India
Contacts
Public ContactDr Manjula Jamaliya
Government Medical Collage, Bhavnagar
Outcome results
None listed