Study will compare which drug is better for prevention of agitation occurring after awakening from anaesthesia given for nasal surgeries

Comparison between dexmedetomidine and midazolam for emergence agitation after nasal surgeries

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/03/008044

Enrollment

Registered

2017-03-08

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA physical status I and II posted for nasal surgeries

Interventions

Intervention1: Group I - Inj dexmedetomidine: Group I would receive Inj dexmedetomidine as 0.5 mcg/kg by intravenous route over 15 minutes and then 0.1mcg/kg/hr as infusion Control Intervention1: Gr

Eligibility

Inclusion criteria

Inclusion criteria: 1.Posted for nasal surgeries 2.ASA physical status I and II 3. Elective surgeries

Exclusion criteria

Exclusion criteria: 1. ASA physical status III and above 2. Heart disease and rhythm disturbances 3. psychiatric illness and anxiety disorder 4. History of post traumatic stress disorder 5. Emergency surgeries 6. Pregnancy 7. History of obstructive sleep apnea

Design outcomes

Primary

Measure	Time frame
To compare incidence of emergence agitation between Inj Dexmedetomidine and Inj Midazolam group.Timepoint: At regaining consciousness, at extubation, every 5 minutes till 30 minutes are over	—

Secondary

Measure	Time frame
To compare perioperative vitals, sedation and recovery profileTimepoint: At baseline, at 5 minutes, at 15 minutes after starting drug infusion then every 15 minutes till end of surgery. sedation and recovery profile at return of consciousness, at extubation and then every 5 minutes for 30 minutes.	—

Countries

India

Contacts

Public ContactDr Pranjali Kurhekar

Shri Sathya Sai Medical College and Research Institute

pranjalikurhekar@gmail.com04427440700

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026