Health Condition 1: null- Preterm infants born between 26 - 30 wks period of gestation, Morbidity and mortality associated with prematurity
Conditions
Interventions
Intervention1: Colostrum: Colostrum obtained from mother in first few days of life
Control Intervention1: Sterile water: Commercially available distilled sterile water
Sponsors
SUDEEP K C
Eligibility
Inclusion criteria
Inclusion criteria: 1. Inborn infants with gestation of 26 to 30weeks admitted under neonatology unit
Exclusion criteria
Exclusion criteria: 1. Parents not willing to give consent 2. Babies born with major life threatening congenital malformations 3.Babies born with severe birth asphyxia 4. If breast milk feeding is contraindicated 5. Triplets and higher birth orders 6. Infants already enrolled in any other research/ study that can influence our study outcomes 4.5.vii Colostrum is unavailable at the time of enrolment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Adverse health outcome Adverse health outcome will be a composite of occurrence of any one of the following : (a) death during hospital stay, (b) culture positive or probable sepsis, (c) necrotizing enterocolitis stage 2 , (d) bronchopulmonary dysplasia , (e) intraventricular hemorrhage grade 2, (f) retinopathy of prematurity needing treatment Timepoint: The outcome will be assessed at time of death , discharge or transfer to another hospital. | — |
Secondary
| Measure | Time frame |
|---|---|
| Bronchopulmonary dysplasiaTimepoint: Till death, discharge or transfer to another hospital;Days on antibioticsTimepoint: Till death, discharge or transfer to another hospital;Definite sepsis Probable sepsisTimepoint: Till death, discharge or transfer to another hospital;Intraventricular HemorrhageTimepoint: Till death, discharge or transfer to another hospital;MortalityTimepoint: Prior to discharge from hospital;Necrotising EnterocolitisTimepoint: Till death , discharge or transfer to another hospital;Retinopathy of prematurityTimepoint: Till death, discharge or transfer to another hospital;Time to full feedTimepoint: Till death, discharge or transfer to another hospital | — |
Countries
India
Contacts
Public ContactDr Praveen Kumar
POST GRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH (PGIMER)
Outcome results
None listed