Effectiveness of transdermal buprenorphine patch on pain relief after spinal surgery

Efficacy of transdermal buprenorphine patch on postoperative pain relief after elective spinal instrumentation surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/03/008018

Enrollment

Registered

2017-03-06

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Postoperative patients of elective spinal instrumentation surgery

Interventions

Intervention1: Transdermal Buprenorphine patch: Transdermal Buprenorphine patch at 10mcg/hr applied 24 hours before surgery and monitored degree of pain for 48 hours postoperatively. Control Intervent

Eligibility

Inclusion criteria

Inclusion criteria: ASA I or ASA II Age between 20-50 yrs Weight between (50-65kg) Patients of either sex. Patients scheduled for elective spinal instrumentation surgery Anticipated duration of surgery 2-3 hrs.

Exclusion criteria

Exclusion criteria: Patient refusal Neurological disorders and history of seizure Patient on CNS depressant drug Known allergic to opioids Opioid dependent patient Hemodynamically compromised patients Patient with hepatic impairment

Design outcomes

Primary

Measure	Time frame
Time to requirement of first rescue analgesic doseTimepoint: 48 hours postoperatively	—

Secondary

Measure	Time frame
Degree and Duration of postoperative analgesia by VAS score. Timepoint: 48 hours postoperatively;Degree of postoperative sedation by RAMSAY Sedation score.Timepoint: 48 hours postoperatively;Frequency of requirement of rescue drug (inj tramadol 2mg/kg) during postoperative period.Timepoint: 48 hours postoperatively;Hemodynamic changes in intraopertive and postoperative periodTimepoint: 48 hours postoperatively;Total intra operative consumption of fentanyl.Timepoint: 48 hours postoperatively	—

Measure

Time frame

Degree and Duration of postoperative analgesia by VAS score. Timepoint: 48 hours postoperatively;Degree of postoperative sedation by RAMSAY Sedation score.Timepoint: 48 hours postoperatively;Frequency of requirement of rescue drug (inj tramadol 2mg/kg) during postoperative period.Timepoint: 48 hours postoperatively;Hemodynamic changes in intraopertive and postoperative periodTimepoint: 48 hours postoperatively;Total intra operative consumption of fentanyl.Timepoint: 48 hours postoperatively

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Countries

India

Contacts

Public ContactDr Pratibha Bhunia

Institute of Postgraduate Medical Education & Research, Kolkata â?? 700020

saikatneuro1972@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026