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Effect of Guided Tissue Regeneration principle with and without bonegrafts in the treatment of human osseous defects

Comparative Evaluation of use of DFDBA alone, DFDBA with Amnion Membrane and DFDBA with PRF membrane in the treatment of human intrabony osseous defects - A Clinicoradiographic study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/03/008012
Enrollment
30
Registered
2017-03-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- 30 Human Intrabony Defects

Interventions

Intervention1: DFDBA: DFDBA is mixed with saline and placed in intrabony defects Control Intervention1: DFDBA with Amnion Membrane: DFDBA is Mixed with saline and Amnion Membrane is cut in dumble shap

Sponsors

Institute of Dental Studies and Technologies
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Individuls of both sexes between age groups 18-60 years. 2) Good general health, not using any systemic medication 3)intrabony periodontal osseous defects with periodontal probing depth (PPD) equal to or more than 5 mm 4)had radiographic evidence of intrabony component equal to or more than 3 mm 5)had no history of any medication affecting the periodontium in the last six months. 6)had not undergone any periodontal treatment for past six months

Exclusion criteria

Exclusion criteria: 1) Individuals with systemic diseases like diabetes mellitus, bone metabolic diseases, platelet deficiencies etc 2)Individuals on anticoagulants or immunosuppressive therapy 3)Pregnant and lactating females 4)Individuals with history of tobacco usage

Design outcomes

Primary

MeasureTime frame
Pocket probing depth - decreases Clinical Attachment Level - Gain Change in Gingival Margin- Apical shift Change in Gingival Recession -Increase Infra I- Decrease Infra II- decrease Defect size - decrease All parameters are taken at baseline, three month and six month.Timepoint: Baseline, 3 month and six month

Secondary

MeasureTime frame
Not ApplicableTimepoint: Not Applicable

Countries

India

Contacts

Public ContactDr Mansi Bansal
drmanishkhatri@yahoo.com9810720335

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026