Health Condition 1: P84- Other problems with newborn Health Condition 2: P84- Other problems with newborn Health Condition 3: null- Sick preterm neonates and term mechanically ventilated neonates receiving intravenous fluids and/or orogastric feeds and are not expected to be fed orally in first 3 days of life.
Conditions
Interventions
Intervention1: Expressed breastmilk: Eight hourly cleaning of oral mucosa will be done by sterile cotton buds soaked in fresh expressed breastmilk (EBM) of the biological mother followed by an instill
Sponsors
Sriparna Basu
Priyanka Gupta Second Investigator
Eligibility
Inclusion criteria
Inclusion criteria: Inborn sick preterm neonates and term mechanically ventilated neonates receiving intravenous fluids and/or orogastric feeds who are not expected to be fed orally in first 3 days of life.
Exclusion criteria
Exclusion criteria: 1.Positive sepsis screen at birth 2.Maternal HIV infection 3.Death of biological mother 4.Major congenital malformation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Combined incidence of nosocomial pneumonia and/or late-onset sepsisTimepoint: At day 28 life or at discharge from hospital, whichever is earlier | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Difference in oral colonizer population with respect to oral care provided 2.Incidence of ventilator associated pneumonia and necrotizing enterocolitis 3.Procedure-related adverse effects 4.Days to achieve full feeds and regain birth weight 5.Exclusive breastfeeding rate at discharge 6.Overall mortality from any cause 7.Duration of hospital stay Timepoint: Till day 28 life or till discharge from hospital, whichever is earlier | — |
Countries
India
Contacts
Public ContactSriparna Basu
Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University Varanasi, India
Outcome results
None listed