Health Condition 1: null- Patients between the ages of 1 to 7 years requiring anaesthesia services for MRI studies
Conditions
Interventions
Control Intervention1: Inj. Dexmedetomidine, Inj. Ketamine, Inj. Propofol: A loading dose of i.v. Dexmedetomidine at 1 µg/kg over 10 minutes is administered followed by i.v. Ketamine at a dose of 1 m
Sponsors
Lokmanya Tilak Municipal Medical College and General Hospital
Eligibility
Inclusion criteria
Inclusion criteria: ASA class I and II
Exclusion criteria
Exclusion criteria: 1) ASA status: III and above 2) Severe cardiovascular or pulmonary pathology 3) History of Propofol allergy 4) Any contraindications for Dexmedetomidine administration 5) Anatomical craniofacial anomaly or suspected difficult airway 6) Evidence of raised intracranial pressure or active seizures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) To study the efficacy of total intravenous anesthesia which is defined by â?¢ Sedation success rate â?¢ Quality of scan as per the radiologist â?¢ Recovery time â?¢ Discharge time Timepoint: every 5 minutes during the procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| To study the safety profile of total intravenous anesthesia, defined by the occurrence of â?¢ Haemodynamic adverse events: Bradycardia Hypotension â?¢ Respiratory adverse events: Bradypnoea (RR 12/min) Desaturation (SpO295%) Laryngospasm Apnoea (cessation of respiration for 20 s) Need of airway intervention measures (jaw thrust, Guedels or laryngeal mask airway, endotracheal tube, or positive pressure ventilation). â?¢ Emergence reaction: determined by the Watcha scale on awakening. Timepoint: At the end of the procedure At the end of the recovery period | — |
Countries
India
Contacts
Public ContactDr Bhuvaneswari Balasubramanian
LTMMC and LTMGH
Outcome results
None listed