Comparison of Two dosage treatments of Primaquine for Cure of Plasmodium Vivax Malaria

Comparative Therapeutic Efficacy Study of Two dosage Regimens of Primaquine for Radical Cure of Plasmodium Vivax Malaria among Adults in Udupi

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/03/007999

Enrollment

Registered

2017-03-03

Start date

Unknown

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Primaquine 0.5mg/kg dose body weight for 14 days: This is the dose recommended by Center for Disease Control. This dose will be administered daily for 14 days Control Intervention1: Pri

Eligibility

Inclusion criteria

Inclusion criteria: 1)Either gender, >= 18 years old, attending adult medical units at Kasturba Hospital, Manipal, and Dr. TMA. Pai Hospital, Udupi, Karnataka 2)Microscopically proven acute P.vivax malaria 3)Fever defined as > 37.5Â°C tympanic or oral temperature or a history of fever within the last 3 days. 4)Written informed consent

Exclusion criteria

Exclusion criteria: 1)Pregnant and/or lactating women 2)Patients with G6PD deficiency

Design outcomes

Primary

Measure	Time frame
Recurrences of malariaTimepoint: 6 Months	—

Secondary

Measure	Time frame
Primaquine levels in the bloodTimepoint: 1 week	—

Countries

India

Contacts

Public ContactDr Kavitha Saravu

Kasturba Medical College Manipal

Kavitha.saravu@manipal.edu9448107636

Outcome results