Health Condition 1: G437- Chronic migraine without aura
Conditions
Interventions
Intervention1: TMS group: Migraine patients who will receive TMS therapy.
Control Intervention1: Sham group: Migraine patients who will receive placebo treatment.
Control Intervention2: Control subjec
Sponsors
All India Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: -The patients diagnosed as Chronic Migraine on the basis of Headache >15 d/month for more than 3 months which has features of migraine for more than 8 days per month ( ICHD- 3rd edition, 2013) -Male/Female -Age: >18 years -Medically refractory to atleast two drugs (like Topiramate and Valproate) -Right handed individuals
Exclusion criteria
Exclusion criteria: -Other forms of headache (e.g., due to previous trauma) -Other comorbidities which prevent intervention ( like hypertension, diabetes,liver and kidney disorder) -History of ferromagnetic implants in head and neck regions, cardiac pacemakers -History of pregnancy, lactation -History of seizure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effect of rTMS on pain status (VAS,Questionnares and Quantitative Sensory Testing) and corticomotor excitability (RMT,MEP,CSP)Timepoint: On completion of therapy and after 1 month follow up (VAS, Questionnare and Quantitative Sensory Testing) | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare corticomotor excitability parameters in healthy control and Chronic MigraineTimepoint: On completion of study.;To compare Quantitative Sensory Testing parameters in healthy control and Chronic Migraine.Timepoint: On completion of study | — |
Countries
India
Contacts
Public ContactAnant Kumar
All India Institute of Medical Sciences New Delhi
Outcome results
None listed