Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium
Conditions
Interventions
Intervention1: Group 1-combined spinal epidural with oral paracetamol group: Parturients will receive 1 gram oral paracetamol 45 mins before combined spinal- epidural block
Control Intervention1: Grou
Sponsors
Government Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1)ASA Grade 1 and 2 2)Age more than 18 years 3)Primigravida Single gestation 4)Cephalic presentation at 36 completed weeks of gestation 5)In early spontaneous labour(cervical dilatation 6)Baseline pain score > 30(on a 0-100 VAS) 7)Able to use PCEA pump 8)Requesting epidural analgesia for labour
Exclusion criteria
Exclusion criteria: 1)Refusal by parturient 2)Parturients who had received parenteral opiods in the last 4 hours 3)Systemic and local sepsis 4)Deranged coagulation profile 5)Parturients having multiple pregnancies and premature labour 6)Obstetrics complications(eg. PROM) Chorioamnionitis 7)Patients with hepatic and renal impairment 8)Unable to swallow oral tablets 9)HELLP syndrome 10)Noncephalic presentations 11)Allgery to study drugs i.e levobupivacaine,fentanyl,paracetamol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hourly total consumption of levobupivacaine + fentanyl mixture, including both continous background infusion plus bolus doses(in ml) starting from 1 hour after ingestion of paracetamol or placebo, for duration of labourTimepoint: Till delivery of baby | — |
Secondary
| Measure | Time frame |
|---|---|
| Maternal satisfaction(VAS) Pain score(VAS) Sensory and motor block characteristics Hemodynamic parameters of mother Foetal heart rate Duration of second stage of labour Mode of delivery Apgar scores Adverse effectsTimepoint: Till delivery of baby | — |
Countries
India
Contacts
Public ContactDr Reecha
Government College and Hospital Chandigarh
Outcome results
None listed