Health Condition 1: M179- Osteoarthritis of knee, unspecified Health Condition 2: null- Patients of osteoarthritis of knee joints
Conditions
Interventions
Intervention1: Biocurcumin: Cap 500mg twice daily orally for 6 weeks
Control Intervention1: Paracetamol: 650mg thrice daily orally for 6 weeks
Sponsors
Maulana Azad Medical college
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients of knee osteoarthritis(Diagnosis based on ACR Criteria) , age 40 - 80 years 2.Patient has not received any NSAIDs or any other analgesic within 24 hours 3.Patients with chronic knee pain (i.e., knee pain at least every other day during the month preceding inclusion) 4.Patients with radiologic knee osteoarthritis (Kellgren-Lawrence grade 2-4) 5.Patients capable of comprehending the study instructions.
Exclusion criteria
Exclusion criteria: 1.Patients with osteoarthritis linked to a metabolic arthropathy 2.Patients with Chondromatosis or villonodular synovitis of the knee 3.History of recent trauma ( 4.Patients who have Inflammatory flare (night pain, joint effusion) 5. Patients who had Corticosteroids injection in the previous month and Hyaluronic acid injection in the evaluated knee during the previous 6 months 6. Patient suffering from serious comorbid conditions(liver failure, kidney failure, uncontrolled cardiovascular diseases) 7. Pregnant patients or breastfeeding women 8. Patients allergic to Ibuprofen or turmeric
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change from baseline in the WOMACÃ? OsteoarthritisÃ? Index pain subscale score at week 6Timepoint: week 6 | — |
Secondary
| Measure | Time frame |
|---|---|
| Change from baseline in the WOMACÃ? OsteoarthritisÃ? Index stiffness and physical functionscores at week 6.Timepoint: week 6 | — |
Countries
India
Contacts
Public ContactDr Bhupinder singh
Maulana Azad Medical College
Outcome results
None listed