A clinical study to understand the pain relieving effects of drug dexmedetomidine in patients who have undergone below knee trauma surgery

Role of dexmedetomidine as adjuvant in postoperative sciatic popliteal and adductor canal analgesia in trauma patients - none

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/02/007955

Enrollment

Registered

2017-02-23

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group II Adductor canal block with 16 ml of a solution having 15 ml 0.5 % ropivacaine and perineurial dexmedetomidine 0.5 microgram per kg constituted in 1 ml normal saline Sciatic

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA physical status I and II of both sex. 2.Age between 18 to 65 years. 3. BMI >= 20 to 4.Scheduled for below knee surgery following acute trauma

Exclusion criteria

Exclusion criteria: 1.Patients having history of substance abuse. 2.Patients with coagulopathy and bleeding disorders. 3.Preexisting peripheral neuropathy. 4.Preexisting local infection at the site of block. 5.Pregnant and lactating women. 6.Inability to understand functioning of PCA pump and VAS (Visual Analogue Scale). 7.Contraindication or allergy to study drug ropivacaine, dexmedetomidine and tramadol. 8.Patients having haemodynamic instability. 9.Patients on regular chronic pain management drugs for the last three months. 10.Patients with history of head injury and/or polytrauma

Design outcomes

Primary

Measure	Time frame
To study tramadol-sparing effect of dexmedetomidine as an adjuvant to ropivacaine in ultrasound guided adductor canal block (ACB) and sciatic popliteal block (SPB) following surgery in below knee surgeryTimepoint: At regular interval upto one hour and then 4 hour 6 hour 12 hour 18 hour 24 hour 30 hour 36 hour 42 hour 48 hour	—

Secondary

Measure	Time frame
To study the hemodynamics, Visual analogue score at rest and on movement Ramsay Sedation Score Quadriceps strength test planter and dorsiflexion sensory analgesia rescue analgesia adverse effects and patient satisfaction score in patients receiving PNB following below knee surgeriesTimepoint: At regular interval upto one hour and then 4 hour 6 hour 12 hour 18 hour 24 hour 30 hour 36 hour 42 hour 48 hour	—

Measure

Time frame

To study the hemodynamics, Visual analogue score at rest and on movement Ramsay Sedation Score Quadriceps strength test planter and dorsiflexion sensory analgesia rescue analgesia adverse effects and patient satisfaction score in patients receiving PNB following below knee surgeriesTimepoint: At regular interval upto one hour and then 4 hour 6 hour 12 hour 18 hour 24 hour 30 hour 36 hour 42 hour 48 hour

—

Countries

India

Contacts

Public ContactVanita Ahuja

Government Medical College and Hospital

jchander@hotmail.com09888443570

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026