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A clinical trial to study the effects of oolong tea as an adjunct to professional cleaning of teeth, in patients with mild to moderate gum and bone disease.

The effect of Oolong tea as an adjunct to non surgical management of chronic periodontitis : A randomised controlled clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/02/007938
Enrollment
60
Registered
2017-02-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Mild to moderate chronic periodontitis

Interventions

Intervention1: Oolong Tea: Oolong tea is a semi-fermented form of the shrub Camellia sinensis. Oolong tea contains flavonoids which are new epigallocatechin esters (p-hydroxybenzoyl and cinnamyl, new

Sponsors

Manipal College of Dental Sciences Manipal
Lead Sponsor
Dr Sonal Nafade
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1) 20- 60 year old males and females 2) With mild to moderate periodontitis - This selection is based according to American Academy of Periodontology (1999) : the classification of severity is as follows: mild : 1-2 mm of clinical attachment loss moderate : 3-4 mm of clinical attachment loss severe : > 5 mm of clinical attachment loss 3) Presence of minimum of 20 teeth

Exclusion criteria

Exclusion criteria: 1) Patient with any systemic diseases, severe liver or kidney disease, or severely ill patients with multiple drug requirements, patients with iron deficiency, anemia, anxiety, bleeding disorders, heart conditions, history of peptic ulcers. 2) Patients consuming any concurrent medications or those who have taken antibiotics or antiinflammatory medication in the past 6 months, similar products or mouthwashes. 3) Patient with any orthodontic or prosthodontic appliance 4) Patient with oral abusive habits such as smoking, alcohol intake and betel nut chewing or any other form of tobacco 5) Pregnant or lactating mothers 6) Patients who have undergone any periodontal treatment in the last 6 months 7) Patients with a high polyphenol diet (green tea, fish)

Design outcomes

Primary

MeasureTime frame
1. Glutathione peroxidase levels in saliva, gingival crevicular fluid and serum 2. Malondialdehyde levels in saliva, gingival crevicular fluid and serum 3. Total antioxidant levels in saliva, gingival crevicular fluid and serum Timepoint: Baseline 1 month after start of study 3 months after start of study

Secondary

MeasureTime frame
1. Gingival index- Loe and Silness (1963) 2. Plaque Index- Silness and Loe (1964) 3. Probing pocket depth 4. Clinical attachment loss 5. % of sites with bleeding on probing. 6. Lobene stain index 7.The estimation of Colony Forming Units (C.F.U) will be done for selective supragingival plaque bacteria such as S. aureus, S. mutans, P. gingivalis, P. intermedia, F. nucleatum, S. salivarius and S. sanguisTimepoint: Baseline 1 month after start of study 3 months after start of study

Countries

India

Contacts

Public ContactDr Sonal Nafade

Manipal College of Dental Sciences, Manipal

get2rupaliagnihotri@gmail.com9900409757

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026