FindTrial
Sign In

Using saliva and Oral smears for early detection of Oral Cancer

Salivary Biomarker and Cytomorphometry for Detection of Oral Squamous Cell Carcinoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2017/02/007917
Enrollment
40
Registered
2017-02-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx Health Condition 2: null- Oral Squamous Cell Carcinoma

Interventions

None listed

Sponsors

Deepika Rathna M
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Case: Patients diagnosed of Oral Squamous Cell carcinoma, yet to undergo any therapeutic intervention Control: Healthy age and gender matched individuals

Exclusion criteria

Exclusion criteria: Patients diagnosed with Parkinsonâ??s disease Patients with history of other malignancies

Design outcomes

Primary

MeasureTime frame
Increased Salivary Biomarker ( s-adenosyl methionine) in patients with oral squamous cell carcinomaTimepoint: 1—

Secondary

MeasureTime frame
- Establishment of baseline Salivary SAM concentration in local population - Elevated SAM concentration in Saliva of OSCC patients compared to normal counterpart - Elevated SAM in patients with Increased N:C ratio - 95% accurate prediction of OSCC by evaluation of N:C ratio and Salivary SAM Timepoint: 1—

Countries

India

Contacts

Public ContactDr Monica C Solomon

Manipal College of Dental Sciences

monica.charlotte@manipal.edu9845701925

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026