Health Condition 1: null- Term neonates and preterm neonates greater than equal to 28 weeks period of gestation admitted to the neonatal intensive care unit.
Conditions
Interventions
None listed
Sponsors
Vishal Vishnu Tewari
Eligibility
Inclusion criteria
Inclusion criteria: Term neonates and preterm neonates > 28 weeks admitted with any one of the following clinical conditions would be enrolled for the study. 1. hypoxic ischemic encephalopathy (HIE), 2. neonatal encephalopathy â?? all etiologies 3. neonatal seizures 4. intraventricular haemorrhage (IVH) 5. meningitis 6. preterm patent ductus arteriosus (PDA) 7. hypotension and shock 8. severe hypoxemic respiratory failure with persistent pulmonary hypertension of newborn (PPHN)
Exclusion criteria
Exclusion criteria: 1. Preterm babies below 28 weeks period of gestation 2. A baby with a congenital CNS anomaly 3. A baby with a lethal congenital anomaly or aneuploidy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neurodevelopmental outcomes on follow-up at 3, 6, 9 and 12 months.Timepoint: 3, 6, 9 and 12 months age | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To monitor the regional cerebral saturation of oxygen (rSO2) in encephalopathic neonates in the neonatal ICU. 2. To target the regional cerebral saturation of oxygen (rSO2) between the range of 55% and 85%. 3. To take corrective measure if the rSO2 goes out of the target range by employing predefined set of actions. 4. To use the measured rSO2 values for making management alterations in the ongoing therapies of enrolled neonates.Timepoint: From enrollment in the study till resolution of encephalopathy | — |
Countries
India
Contacts
Public ContactVishal Vishnu Tewari
Armed Forces Medical Services
Outcome results
None listed