Skip to content

TO check the efficacy of guava leaf extract containing mouthwash in treating the gum disease.

Evaluation of mouthrinse containing guava leaf extract as a part of comprehensive oral care regimen - A randomized placebo controlled clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/02/007898
Enrollment
50
Registered
2017-02-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- moderate to severe gingivitis

Interventions

Intervention1: guava leaf extract based mouthrinse: guava leaf will be dried and then the extract will be taken and the mouthwash will be formulated.Patient will be prescribed the mouthwash after the

Sponsors

Dr Namratha Nayak
Lead Sponsor
Manipal University
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1. Presense of a minimum of 20 functional teeth. 2. Patients with chronic generalized marginal gingivitis. 3. Patients within the age group of 18-50 years.

Exclusion criteria

Exclusion criteria: 1. Subjects with removable or fixed orthodontic appliances or prosthesis. 2. Subjects who have been prescribed antibiotics or anti-inflammatory drugs in the prior 3 months that might interfere with the plaque formation. 3. Subjects who have undergone periodontal treatment in the previous 6 months 4. Subjects who consume a high polyphenol diet (including green tea or soya diet) or known allergic. 5. Subjects who have a tobacco related habit 6. Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
The anti microbial and anti oxidant effect of guava leaf extract based mouth rinse will be evaluated by assessing saliva and plaque samples and improvement in the clinical parameters.Timepoint: recall intervals of 1 ,2 and 3rd month.

Secondary

MeasureTime frame
Gingival index Plaque indexTimepoint: 1 2 and 3 months

Countries

India

Contacts

Public ContactDr Namratha Nayak

Manipal College Of Dental Sciences,Manipal

jothimv@gmail.com9845208532

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 20, 2026