Health Condition 1: null- Patients of age 18 years or more of either sex presenting with acanthosis nigricans
Conditions
Interventions
Intervention1: Canthexâ?¢: Capsule containing fixed dose combination of alpha lipoic acid 200 mg, biotin 5 mg, calcium pantothenate 200 mcg and zinc sulphate 25 mg, each capsule to be taken twice dail
Sponsors
Department of Dermatology Medical College Kolkata
Eligibility
Inclusion criteria
Inclusion criteria: All patients aged more than 18 years of either sex presenting with Acanthosis Nigricans
Exclusion criteria
Exclusion criteria: Pregnant and lactating women Patients with Renal and/or hepatic compromise Patients not consenting to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A.Clinical effectiveness of Canthex versus Metformin by 1.Severity of neck lesions of Acanthosis nigricans 2.Neck texture of Acanthosis nigricans 3.Physician global assessment score B.Safety of two treatment arms 1. By checklist for adverse events 2. CDSCO ADR reporting form 3. Laboratory investigationsTimepoint: Baseline and at 4, 8 and 12 weeks after randomization | — |
Secondary
| Measure | Time frame |
|---|---|
| A.Improvement in Insulin resistance with Metformin versus Canthexâ?¢ by 1.Body Mass Index 2.Waist Circumference 3.Fasting Blood Sugar 4.Fasting Insulin level 5.Fasting serum lipids B.Quality of life in the two treatment arms by Dermatology Life Quality Index (DLQI)Timepoint: Baseline and at 4, 8 and 12 weeks after randomization | — |
Countries
India
Contacts
Public ContactDr Adrija Datta
Department of Dermatology, Medical College, Kolkata, West Bengal
Outcome results
None listed