Health Condition 1: null- Children with acute onset diarrhea of 48 hrs duration, some (mild and moderate) to severe dehydration, and aged between 12 months to 5 years
Conditions
Interventions
Intervention1: Nitazoxanide: Syrup nitazoxanide administered twice daily (100mg in 12-47 months
200mg in â?¥4 yrs) for 3 days
Control Intervention1: Placebo: Similar product (colour and tase being similar) to the active drug being adminstered twice daily for 3 days
Sponsors
Department of Pediatrics HiTech Medical College Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Children with acute onset diarrhea of <48 hrs duration, some (mild and moderate) to severe dehydration, and aged between 12 months to 5 years were eligible for inclusion
Exclusion criteria
Exclusion criteria: Children with dysentery, severe malnutrition (weight for height <3SD of WHO growth-chart), co-existing systemic illnesses and chronic diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Duration (in hrs) of acute diarrheaTimepoint: Time of discharge | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Duration (in hrs) of hospitalizationTimepoint: Time of discharge;2. Duration (in hrs) of vomitingTimepoint: Time of discharge discharge;3. Duration (in hrs) of feverTimepoint: Time of discharge;4. Proportion of children requiring parenteral rehydrationTimepoint: Time of discharge;5. Any adverse effectsTimepoint: Time of discharge | — |
Countries
India
Contacts
Public ContactSamarendra Mahapatro
Hi-Tech Medical College & Hospital
Outcome results
None listed