FindTrial
Sign In

A STUDY ON CHILDREN SUFFERING FROM NUTRITIONAL RICKETS AGED 6 MONTHS TO 5 YEARS COMPARING A LOWER DOSE OF VITAMIN D GIVEN AS A SINGLE ORAL DOSE FOR TREATMENT (90,000IU) WITH THE STANDARD DOSE (3,00,000 IU)

TO COMPARE THE EFFICACY OF 90,000 IU AND 3,00,000 IU ORAL SINGLE DOSE VITAMIN D FOR TREATMENT OF NUTRITIONAL RICKETS IN CHILDREN AGED 6 MONTHS TO 5 YEARS- A RANDOMIZED CONTROLLED TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/02/007791
Enrollment
106
Registered
2017-02-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- CHILDREN AGED 6 MNTHS TO 5 YRS WITH NUTRITIONAL RICKETS EXCLUDIN SEVERE SYSTEMIC ILLNESS,ON CALCIUM OR VITAMIN D SUPPLEMENTS,FEATURES OF MALABSORPTION

Interventions

Intervention1: VITAMIN D: 90,000 IU SINGLE STAT ORAL DOSE IN THE FORM OF TABLETS followed by calcium syrup at 50mg/kg/day for three months Control Intervention1: VITAMIN D: 3,00,000 IU ORAL SINGLE STA

Sponsors

CHACHA NEHRU BAL CHIKITSALYA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: PATIENTS AGED 6 MONTHS TO 5 YEARS WITH BIOCHEMICAL AND RADIOLOGICAL DIAGNOSIS OF RICKETS PRESENTING TO OPD OR ADMITTED AT IPD IN DEPARTMENT OF PEDIARICS AT CHACHA NEHRU BAL CHIKITSALYA

Exclusion criteria

Exclusion criteria: 1)PATIENTS WITH SUSPECTED OR CONFIRMED DIAGNOSIS OF MALABSORPTION 2)PATIENTS WITH SEVERE SYSTEMIC ILLNESS COMPROMISING ORAL INTAKE(TACHYCARDIA,TACHYPNEA,SHOCK,WEAK PERIPHERAL PULSES) 3)PATIENTS WHO HAVE TAKEN CALCIUM OR VITAMIN D SUPPLEMENT IN LAST 6 MONTHS 4)PATIENTS WITH CLINICAL OR BIOCHEMICAL MARKERS SUGGESTIVE OF RICKETS OTHER THAN NUTRITIONAL RICKETS

Design outcomes

Primary

MeasureTime frame
RADIOLOGICAL HEALING AT 90 DAYSTimepoint: RADIOLOGICAL HEALING AT 90 DAYS—

Secondary

MeasureTime frame
1)SIDE EFFECT PROFILE USING CALCIUM/CREATININE i.e. HYPERCALCIURIATimepoint: 7-10th DAY,30-37th DAY,90-97th day;DECLINE IN ALP LEVELTimepoint: 30-37TH DAY,90-97TH DAY;DECLINE IN PTH LEVELTimepoint: 90 DAYS;INCREASE IN 25(OH)DTimepoint: 90 DAYS—

Countries

India

Contacts

Public ContactVineeta Yadav

CHACHA NEHRU BAL CHIKITSALYA

goelmedha@gmail.com9643308219

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026