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Use of Peroperative Antibiotics in Patients Undergoing Surgery For Breast Cancer

Effect Of Antibiotic Prophylaxis In Patients Undergoing Modified Radical Mastectomy - A Randomized Double-Blinded Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/02/007790
Enrollment
200
Registered
2017-02-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with proven diagnosis of carcinoma breast planned for modified radical mastectomy as decided by institute tumor board

Interventions

Intervention1: INJECTION CEFAZOLIN: 1gm Cefazolin diluted in 10ml of distilled water and administered intravenously at the time of induction of anaesthesia Control Intervention1: NORMAL SALINE: 10 ml

Sponsors

JIPMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: PATIENTS WHO ARE DIAGNOSED CASES OF CARCINOMA BREAST WHO ARE PLANNED TO UNDERGO MODIFIED RADICAL MASTECTOMY AS DECIDED BY THE INSTITUTE TUMOR BOARD

Exclusion criteria

Exclusion criteria: Exclusion criteria 1. Hypersensitivity to intravenous Cefazolin 2. Patients receiving antibiotics for some other reason 3. Patients with local skin infections at the site of surgery 4. Patients on steroids 5. Immunosuppressive disease(HIV)

Design outcomes

Primary

MeasureTime frame
Rate of Surgical Site Infection according to CDC definitionTimepoint: 30 Days—

Secondary

MeasureTime frame
Detecting potential risk factors in the development of surgical site infectionTimepoint: 30 Days—

Countries

India

Contacts

Public ContactDr Galidevara Indira

JIPMER

alysmanwar@yahoo.co.in9488820340

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026