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Role of steroids in viral respiratory tract infections in children

Role of Steroids in Acute Viral Lower Respiratory Tract Infections: A Randomized Double Blind Placebo Controlled Trial - SAVI-LRTI trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/02/007782
Enrollment
100
Registered
2017-02-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- children age group from completed 1 month to 30 months with viral LRTIS (bronchiolitis,viral pneumonia)

Interventions

Intervention1: inj. hydrocortisone: 100mg vial 5mg/kg/dose thrice daily for 3 days Control Intervention1: Inj cefotaxime: 250mg vial 5mg/kg/day thrice daily for 3 days. similar looking vial withrespec

Sponsors

Laxman hanmanthappa bidari
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: children aged from completed 1 to 30 months with clinically diagnosed acute viral LRTIS pneumonia or bronchiolitis admitted in PICU with moderate and severe respiratory distress and/or failure

Exclusion criteria

Exclusion criteria: 1.suspected and/or diagnosed bacterial pneumonia 2.pneumonia with parapneumonic effusion 3.pulmonary oedema (cardiogenic and non cardiogenic) 4.systemic infection causing respiratory infection 5.cardiac disease 6. children who have received any systemic steroids for more than 24 hours prior to admission chronic or recurrent lung diseases debilitating neurological illnesses

Design outcomes

Primary

MeasureTime frame
length of hospital stayTimepoint: Admission to discharge

Secondary

MeasureTime frame
duration of wheeze duration of respiratory distress duration of oxygen therapy need of ventilationTimepoint: Admission to discharge

Countries

India

Contacts

Public ContactDr GOVIND BENKATTI

DR. BIDARIS ASHWINI INSTITUTE OF CHILD HEALTH AND RESEARCH CENTER

govind.pgi@gmail.com7760471840

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026