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Effect Of General Anaesthesia On Blood Glucose In Diabetic Patients - Comparision of two drugs Etomidate And Thiopentone Sodium.

Effect Of Induction Of General Anaesthesia On Blood Glucose In Diabetic Patients - Comparision Between Etomidate And Thiopentone Sodium : A Randomised Control Study. - -

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/02/007752
Enrollment
100
Registered
2017-02-01
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: Etomidate: 2mg given intravenously every 10 sec till patient becomes unconscious and there is loss of response to verbal commands Control Intervention1: Thiopentone sodium: 30 mg given

Sponsors

Nizams Institute and Medical Sciences
Lead Sponsor
Dr Indira Gurajala
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1. Diabetic patients 2. Age group 30- 65 years 3. Surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: 1. Endocrine disorders 2. Renal disease 3. Hepatic disease 4. Pregnancy 5. Patients receiving steroids, beta blockers 6. Alcohol consumption 1 week before surgery

Design outcomes

Primary

MeasureTime frame
Glucose levelTimepoint: Baseline at induction of GA, at 15 mins, 30 mins,1,2,4,8,12,24 hrs after the administration of the induction agent etomidate or thiopentone.

Secondary

MeasureTime frame
Side effects such as haemodynamic instability, myoclonus, pain on injection and hiccoughsTimepoint: At induction of GA

Countries

India

Contacts

Public ContactIndira Gurajala

Nizams Institute of Medical Sciences, Hyderabad

ramdaspallymahesh@gmail.com9490401148

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026