Very low current brain stimulation (Transcranial Direct Current Stimulation) to improve upper limb and lower limb weakness in stroke patients.

A randomized, double blind, sham controlled study of transcranial direct current stimulation (tDCS) as an augmentation intervention for the attenuation of motor deficits in patients with arterial stroke. - STDCS

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/01/007733

Enrollment

Registered

2017-01-20

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I639- Cerebral infarction, unspecified Health Condition 2: I619- Nontraumatic intracerebral hemorrhage, unspecified

Interventions

Intervention1: True Transcranial Direct Current Stimulation: tDCS will be administered twice daily,at an interval of approximately 5 hours. The tDCS session will be approximately 30 minutes in duratio

Eligibility

Inclusion criteria

Inclusion criteria: 1 Occurrence of first, ischemic or hemorrhagic, supratentorial stroke with focal motor deficits 2 Premorbid Modified Rankin Scale is less than 3

Exclusion criteria

Exclusion criteria: 1 Presence of global aphasia 2 Major unstable co-morbidity, including medical and neuropsychiatric co morbidity (e.g. delirium, depression, recent myocardial infarction, unstable angina etc) 3 Past or current history of major neuropsychiatric illnesses e.g., Alzheimerâ??s disease, Parkinsonâ??s disease, Epilepsy, Schizophrenia, Bipolar disorder, Major Depressive Disorder 3 Current or recent (less than 3 months) use of psychotropic medication such as antidepressants, antipsychotics and anticonvulsant drugs for more than 7 consecutive dayy. Anxiolytic and hypnotic medications are however permitted. 4 Inability to perform study procedures because of uncorrected visual impairment or uncorrected hearing impairment. 5 Presence of cerebral or cardiovascular implants. 6 Electroconvulsive therapy, repetitive transcranial magnetic stimulation, or any other brain stimulation therapy in the last six months

Design outcomes

Primary

Measure	Time frame
Fugl Meyer Assessment Jebson Taylor Assessment Barthel IndexTimepoint: First assessment- before the first tDCS session Second assessment- after the last tDCS session Third assessment- two weeks after the last tDCS session	—

Secondary

Measure	Time frame
Digit span, forwards and backwards Serial subtraction test Category fluency test Spatial span Tower of London Complex figure test Complex passage Paired word associate learning Hamilton Anxiety Rating Scale (HAM-A) Hamilton Rating Scale for Depression (HAM-D) Timepoint: First assessment- before the first tDCS session Second assessment- after the last tDCS session Third assessment- two weeks after the last tDCS session	—

Measure

Time frame

Digit span, forwards and backwards Serial subtraction test Category fluency test Spatial span Tower of London Complex figure test Complex passage Paired word associate learning Hamilton Anxiety Rating Scale (HAM-A) Hamilton Rating Scale for Depression (HAM-D) Timepoint: First assessment- before the first tDCS session Second assessment- after the last tDCS session Third assessment- two weeks after the last tDCS session

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Countries

India

Contacts

Public ContactEkta Franscina Pinto

National Institute of Mental Health and Neurosciences

andradec@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 15, 2026