Health Condition 1: null- Oral submucous Fibrosis Health Condition 2: K121- Other forms of stomatitis
Conditions
Interventions
Intervention1: Tablet Curcumin 300 mg: Tablet was administerd orally thrice daily for 9 months
Intervention2: Group A: Tablet Curcumin & Piperine 300 mg: 300 mg Tablet was administered orally thrice d
Sponsors
Maulana Azad Institute of Dental Sciences
Indian Council of Medical Research
Eligibility
Inclusion criteria
Inclusion criteria: •Clinically & Histopathologically proven case of OSMF 1)A positive history of chewing areca nut or one of its commercial preparation, difficulty in swallowing and chewing, and burning sensation on eating spicy foods.81 2)Restricted mouth opening and changes in the oral mucous membrane including the presence of palpable vertical fibrous bands, stiffness and blanching.81 •Positive habit history of tobacco, smoking, betel quid, and alcohol.
Exclusion criteria
Exclusion criteria: •Those who were not willing to participate. •Patients who were already undertaking some treatment for existing potentially malignant oral disorder. •Patients with severe systemic disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of burning sensation score, mouth opening, tongue protrusion and cheek flexibility between groups and within groupTimepoint: Patients were assessed clinically every 4 weeks for 9 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Reporting of Malignant transformation over period of 9 monthsTimepoint: individuals were assesses every 4 weeks for 9 months. in case of any suspicion, biopsy was done. | — |
Countries
India
Contacts
Public ContactDr Shikha
Maulana Azad Institute of Dental Sciences
Outcome results
None listed