Health Condition 1: null- Rheumatoid Arthritis patients with chronic periodontitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Subjects willing to give written informed consent 2. Patients with rheumatoid arthritis (RA) diagnosed according to the revised 2010 ACR criteria and with joint involvement score of 3 (4-10 small joints with or without involvement of large joints) for the classification of RA 3. Patients with moderate chronic periodontitis (at least 2 interproximal sites not on the same tooth with probing depth of >=5 to 4. Patients under similar medication for rheumatoid arthritis.
Exclusion criteria
Exclusion criteria: 1. Mild and Severe chronic periodontitis 2. Antibiotic therapy and periodontal therapy in last 3 months 3. History of systemic diseases 4. History of hypersensitivity to mouthwash 5. Using any mouthwash/rinse in the last month 6. Smoking 7. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in probing depth and clinical attachment loss and reduction in the levels of anti-citrullinated protein antibody (ACPA), Rheumatoid factor, C-reactive protein and erythrocyte sedimentation rate (ESR)Timepoint: 6 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction in the levels of anti-citrullinated protein antibody (ACPA), Rheumatoid factor, C-reactive protein and erythrocyte sedimentation rate (ESR)Timepoint: 6 weeks | — |
Countries
India
Contacts
Meenakshi Ammal Dental College and Hospital