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A clinical trial to study the effect of periodontal treatment on rheumatoid arthritis disease

Efficacy of Turmix mouthwash as an adjunct to non-surgical periodontal therapy among the patients with chronic periodontitis and rheumatoid arthritis attending a private rheumatology clinic in Guntur city- A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/01/007713
Enrollment
40
Registered
2017-01-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Rheumatoid Arthritis patients with chronic periodontitis

Interventions

Intervention1: Group A: Scaling and root planing in adjunct with turmix mouthwash Control Intervention1: Group B: Scaling and root planing in adjunct with 0.2% chlorhexidine mouthwash Control Interven

Sponsors

Divvi Anusha
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subjects willing to give written informed consent 2. Patients with rheumatoid arthritis (RA) diagnosed according to the revised 2010 ACR criteria and with joint involvement score of 3 (4-10 small joints with or without involvement of large joints) for the classification of RA 3. Patients with moderate chronic periodontitis (at least 2 interproximal sites not on the same tooth with probing depth of >=5 to 4. Patients under similar medication for rheumatoid arthritis.

Exclusion criteria

Exclusion criteria: 1. Mild and Severe chronic periodontitis 2. Antibiotic therapy and periodontal therapy in last 3 months 3. History of systemic diseases 4. History of hypersensitivity to mouthwash 5. Using any mouthwash/rinse in the last month 6. Smoking 7. Pregnancy

Design outcomes

Primary

MeasureTime frame
Reduction in probing depth and clinical attachment loss and reduction in the levels of anti-citrullinated protein antibody (ACPA), Rheumatoid factor, C-reactive protein and erythrocyte sedimentation rate (ESR)Timepoint: 6 weeks

Secondary

MeasureTime frame
Reduction in the levels of anti-citrullinated protein antibody (ACPA), Rheumatoid factor, C-reactive protein and erythrocyte sedimentation rate (ESR)Timepoint: 6 weeks

Countries

India

Contacts

Public ContactDivvi Anusha

Meenakshi Ammal Dental College and Hospital

drpchaly@gmail.com9840330834

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026