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Study to asses the effect of a drug (anti-cholinergic) on insulin levels in pre-diabetics and comparison with healthy people

Impact of Anticholinergics On Insulin Response To Oral Glucose Load In Patients With Impaired Glucose Tolerance

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2017/01/007703
Enrollment
16
Registered
2017-01-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Impaired Glucose Tolerance

Interventions

Intervention1: Hyoscine Butyl-Bromide (20mg): P/O Tablet single dose

Sponsors

Institute of Post Graduate Medical Education Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Informed consent 2) Impaired Glucose Tolerance subjects ( Fasting PG: 100 â?? 125 mg/dL; 2h PP PG: 140-199 mg/dL) 3) Age, gender and weight matched controls

Exclusion criteria

Exclusion criteria: 1) Pregnancy or breastfeeding 2) Immunocompromised 3) Contraindication for anticholinergic agents 4) Pre-existing gastro-intestinal disorders 5) Impaired renal or hepatic functions 6) Diabetes Mellitus 7) Concomitant drugs

Design outcomes

Primary

MeasureTime frame
Plasma Glucose & Serum Insulin levelsTimepoint: 0min 30min 60min 90min 120min—

Secondary

MeasureTime frame
HOMA-IRTimepoint: 0min—

Countries

India

Contacts

Public ContactSandeep Lahiry
ilatimc@gmail.com9432879503

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026