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Comparison of general anaesthesia using Desflurane at low flow (1 L/min)and medium flow rates (2L/min)

Comparison of low (1 L/min) with medium (2 L/min) flow anaesthesia using Desflurane: effects on Oxygen concentration, Desflurane consumption and recovery profile

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/01/007699
Enrollment
60
Registered
2017-01-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- American Society of Anesthesiologists status I and II

Interventions

Intervention1: 1 L/min: Desflurane anaesthesia with fresh gas flow of 1 L/min Control Intervention1: 2 L/min: Desflurane anaesthesia with fresh gas flow of 2 L/min

Sponsors

PGIMER DR RAM MANOHAR LOHIA HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA status I and II. 2.Age group 18 to 60 years. 3.Posted for elective surgery under general anaesthesia. 4.Duration of the anaesthesia 90 to 180 minutes approximately

Exclusion criteria

Exclusion criteria: 1.Laparoscopic surgery. 2.Pregnancy. 3.Obesity with BMI > 30.

Design outcomes

Primary

MeasureTime frame
To compare the inspired and expired oxygen and desflurane concentrations in low flow(1 L/min) with medium flow (2 L/min) desflurane anaesthesiaTimepoint: Baseline(pre operative) 10 mins 20 mins 30 mins 60 mins 90 mins 120 mins 150 mins 180 mins ABG- Baseline 20 mins after switching to low flow 20 mins before reversal—

Secondary

MeasureTime frame
To compare the recovery profile and desflurane consumption of the patients of low flow (1 L/min) with medium flow (2 L/min) desflurane anaesthesiaTimepoint: MODIFIED ALDRETE SCORE - 5 mins 15 mins 30 mins—

Countries

India

Contacts

Public ContactNeerja Banerjee

PGIMER, Dr. Ram Manohar Lohia Hospital

neerja.banerjee@gmail.com9810517575

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026