Health Condition 1: null- suffering from Osteoarthritis knee
Conditions
Interventions
Intervention1: Upanaha: Upanaha (warm poultice) with Vachadi Upanaha churna once a day for 14 days
Control Intervention1: Nil: Nil
Sponsors
Central Council For Research in Ayurvedic Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients of either sex aged between 35 and 65 years. 2. Subjects having VAS score for knee pain between 45-74 mm (moderate pain) 3. Clinical and radiological evidence of Osteoarthritis knee (Unilateral/ bilateral) as per ACR criteria (i) knee pain, (ii) at least one of three (a) Age > 50 years (b) stiffness (c) Crepitus (iii) Osteophytes 4. Radiographical changes as per Grade I to III of Kellgren& Lawrence Radiological scale 5. Able and willing to participate and provide signed informed consent
Exclusion criteria
Exclusion criteria: 1. Patients with Grade IV Kellgren& Lawrence Radiological scale 2. History of any trauma/ fractured joint / surgical/diagnostic intervention with reference to the affected joint(s). 3. H/O monoarthritis/ polyarthritis other than Osteoarthritis Knee such as gouty arthritis, rheumatoid arthritis and psoriatic arthritis etc. 4. Any unstable cardio-vascular disease. 5. Patients with uncontrolled Hypertension ( >160/100 mmHg) 6. Patients with uncontrolled Diabetes Mellitus having HbA1C >7.5% 7. Patients with evidence of malignancy. 8. Patients with any concurrent hepatic disorder (defined as liver enzymes SGOT/SGPT >2 times upper normal limit) or Renal Disorders (defined as S.Creatinine >1.4mg/dl) or Pulmonary Dysfunction 9. The patient has been administered any chondroprotective drugs, intra-articular injection into the affected joint or systemic medication with corticosteroids during the preceding 3 months. 10. Pregnant / lactating woman. 11. Patients who are currently participating in any other clinical trial. 12. Any other condition which the Principal Investigator thinks may jeopardize the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| â?¢ Change in the visual analogue scale (VAS) for pain in last 48 hrs â?¢ Change in the visual analogue scale (VAS) for stiffness in last 48 hrs â?¢ Change in WOMAC total score â?¢ Change in WOMAC subscales (pain, function and stiffness) Timepoint: â?¢ Change in the visual analogue scale (VAS) for pain in last 48 hrs from baseline to 14th day â?¢ Change in the visual analogue scale (VAS) for stiffness in last 48 hrs from baseline to 14th day â?¢ Change in WOMAC total score from baseline to 14 th day â?¢ Change in WOMAC subscales (pain, function and stiffness) from baseline to 14 th day | — |
Secondary
| Measure | Time frame |
|---|---|
| NilTimepoint: Nil | — |
Countries
India
Contacts
Public ContactDr Deepa Makhija
Central Ayurveda Research Institute for Cardio-vascular Diseases
Outcome results
None listed