Health Condition 1: null- Health condition â??Breast and ovarian cancer patients carriers of BRCA ½ genes. Problem studied â??Early metastasis and rapid growth of cancer due to inherited susceptibility genes Health Condition 2: C50- Malignant neoplasm of breast
Conditions
Interventions
Intervention1: A. Suvarna Bhasmadi Vati: Study group patients (1) would have completed their surgery and are on chemotherapy or have completed chemotherapy will start the intervention with following A
Sponsors
Dr S P Sardeshmukh
Eligibility
Inclusion criteria
Inclusion criteria: Genetically predisposed patients (BRCA1/2 mutation carriers) with breast or ovarian cancer within 6 months to 1 year of diagnosis. During this period they would have completed conventional cancer treatment.Patients with stage I to IV of disease will be included
Exclusion criteria
Exclusion criteria: Patients with BRCA1/2 mutation reporting 1 year and more after diagnosis will be excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| For assessment of recurrence or metastasis, clinical examination, mammography, PET CT, CT scan (Abdomen and pelvis), 2D ECHO, and other imaging techniquesTimepoint: Day 0 (Before starting Ayurvedic medicines),After 6 months of Ayurvedic treatment, After 1 year of Ayurvedic medicines,After 1.5 years of Ayurvedic treatment, After 2 years of Ayurvediic medicines, After 2.5 years of Ayurvedic treatment, After 3 yeras of Ayurvedic medicines | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood SugarTimepoint: Day 0 ( before starting Ayurvedic treatment);Changes in HeamogramTimepoint: Day 0 (Before starting Ayurvedic medicines), After 1 year of Ayurvedic medicines, After 2years of Ayurvediic medicines, After 3 yeras of Ayurvedic medicines;Changes in Immune parameters (cytokines) like IL 1, IL- 6, IL-8, IL -10, IFN Gamma, TNF AlphaTimepoint: Day 0 (Before starting Ayurvedic medicines), After 1 year of Ayurvedic medicines, After 2years of Ayurvediic medicines, After 3 yeras of Ayurvedic medicines;Changes in Karnofsky score â?? For performance statusTimepoint: Day 0 (Before starting Ayurvedic medicines), After 1 year of Ayurvedic medicines, After 2years of Ayurvediic medicines, After 3 yeras of Ayurvedic medicines;Changes in Kidney Function TestTimepoint: Day 0 (Before starting Ayurvedic medicines), After 1 year of Ayurvedic medicines, After 2years of Ayurvediic medicines, After 3 yeras of Ayurvedic medicines;Changes in Liver Function TestTimepoint: Day 0 (Before starting Ayurvedic medicines), After 1 year of Ayurvedic medicines, After 2years of Ayurvediic medicines, After 3 yeras of Ayurvedic medicines;Changes in Oxidative Stress by Catalase, SOD, GST and GSTP1 Hypermethylation Timepoint: Day 0 (Before starting Ayurvedic medicines), After 1 year of Ayurvedic medicines, After 2years of Ayurvediic medicines, After 3 yeras of Ayurvedic medicines;Changes in Quality of Life Questionnaires (QLQ C30 and BR23) of EORTC for Quality of LifeTimepoint: Day 0 (Before starting Ayurvedic medicines), After 1 year of Ayurvedic medicines, After 2years of Ayurvediic medicines, After 3 yeras of Ayurvedic medicines | — |
Countries
India
Contacts
Public ContactDr Pradnya Chaugule
Integrated Cancer Treatment and Research Centre
Outcome results
None listed