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Premedication with oral clonidine,dexmedetomidine or melatonin in children undergoing surgery

A COMPARATIVE EVALUATION OF ORAL CLONIDINE, DEXMEDETOMIDINE AND MELATONIN AS PREMEDICANTS IN PAEDIATRIC PATIENTS UNDERGOING SUB-UMBILICAL SURGERIES - Premedication,children,clonidine,dexmedetomidine, melatonin

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/01/007682
Enrollment
105
Registered
2017-01-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients of age 2 - 14 years, either sex, American society of anaesthesiologists (ASA) grade I and II posted for elective sub umbilical surgery under general anaesthesia were included in the study

Interventions

Intervention1: clonidine 5 mcg/kg orally.: All the premedicants were given with syp. Paracetamol 2-2.5 mg/kg to be easily drinkable 45 min before surgery Intervention2: dexmedetomidine 3 mcg/kg orally

Sponsors

Himalayan Institute of Medical SciencesSwami Ram University
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of age 2 - 14 years, either sex, American society of anaesthesiologists (ASA) grade I and II posted for elective sub umbilical surgery under general anaesthesia were included in the study.

Exclusion criteria

Exclusion criteria: Exclusion criteria • Age >14 years • ASA grade III and IV. • Any systemic disease that compromises any cardiovascular, • respiratory or neurological function. • History of upper and lower airway disease or infection. • Coagulation disorders. • Known allergy to the study drugs. • History of sleep apnoea. • The need for postoperative ventilation.

Design outcomes

Primary

MeasureTime frame
Preoperative sedation and anxiolysisTimepoint: Preoperative

Secondary

MeasureTime frame
Postoperative analgesia, emergence delirium and agitation.Timepoint: 0, 30 min, 1, 2, 4, 6, 8, 12, 24 hours postoperatively

Countries

India

Contacts

Public ContactVeena Asthana

Himalayan Institute of Medical Sciences,

turabali011@gmail.com9470001223

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026