Health Condition 1: null- Patients of either sex, 18-60 years of age, ASA grade I & II undergoing elective percutaneous nephrolithotomy under general anaesthesia upto 24 hours postoperatively.
Conditions
Interventions
Intervention1: Cap .Tramadol100mg: The drug will be filled in identical looking soft gelatin capsule from pharmacy and administered one hour prior to induction with sip of water
Intervention2: Cap Pre
Sponsors
Himalayan Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: Patients of either sex, 18-60 years of age, ASA grade I & II undergoing elective percutaneous nephrolithotomy under general anaesthesia
Exclusion criteria
Exclusion criteria: Exclusion Criteria - Age 60years - ASA grade III & IV - History of significant cardiac diseases like previous MI, arrhythmias, high A V conduction blocks, uncontrolled hypertension, angina. - History of chronic use of beta- blockers - Sleep apnoea - Significant liver dysfunction - History of chronic opioid use, - Patients with renal failure ( higher serum creatinine levels >= 1.5mg%, urine 3 at night or >8 in 24 hours) / transurethral resection of prostate for benign prostatic hyperplasia -Hypersensitivity to any of the study drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and severity of CRBDTimepoint: Incidence and severity of CRBD at 0hr,30min,2 hrs,4 hrs,6 hrs ,12 hrs & 24 hrs postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| Preoperative sedation Haemodynamic variability Adverse effects Amount of postoperative fentanyl required by PCA.Timepoint: Preoperative before induction Intraoperative Postoperatively 24 hours | — |
Countries
India
Contacts
Public ContactSanjay Agrawal
Himalayan Institute of Medical Sciences
Outcome results
None listed