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Pain relief for knee replacement surgery

Adductor canal block for post-operative analgesia after total knee replacement: a randomized controlled trial to study the effect of addition of dexmedetomidine to ropivacaine

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/01/007657
Enrollment
100
Registered
2017-01-10
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Those scheduled for knee replacement surgery

Interventions

Intervention1: Adductor Canal Block, Ropivacaine, Dexmedetomidine: The block will be given with ropivacaine alone (0.3%) without any additives in a total volume of 20 ml as a single injection in the a

Sponsors

Army Hospital Research and Referral Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I-III; BMI 20-30 kg/m2

Exclusion criteria

Exclusion criteria: Contraindication to subarachnoid block or allergy to any of the study drugs; Known coagulopathy, local infection at block site; Patients in whom the nerve block could not be performed at per the procedure described in the methodology; Renal dysfunction

Design outcomes

Primary

MeasureTime frame
The aim of this study is to compare the duration of analgesia of adductor canal block using ropivacaine with and without dexmedetomidine after total knee replacement.Timepoint: 15 min, 30 min, 45 min, 60 min, 6 hr, 12 hr, 18 hr, 24 hr

Secondary

MeasureTime frame
The secondary outcomes will be the total 24 hr opioid consumption, success of early ambulation, level of patient satisfaction, and any adverse effects following the study intervention.Timepoint: Medical Research Council Scale as 0-5 at 6, 12, 18 and 24 hr after the block.

Countries

India

Contacts

Public ContactRAKHEE GOYAL

Professor Anaesthesia

rakheegoyalkumar@gmail.com7798225637

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026